Ciprofloxacin (Cipro) for Urinary Tract Infection
Fluoroquinolone antibiotic ciprofloxacin (Cipro) is widely used to treat Urinary Tract Infections (UTIs) because it reaches high urinary concentrations, has an excellent activity against most uropathogens, and is available in oral and intravenous formulations.
Ciprofloxacin dosage for UTI
Children 1–17 years of age:
Complicated UTIs and pyelonephritis: 10-20 mg/kg (up to 750 mg) every 12 hours for 10-21 days.
Cystitis (bladder indection): 250 mg every 12 hours for 3 days.
Mild to moderate UTIs:
Complicated UTIs, pyelonephritis: 500 mg every 12 hours for 7-14 days.
How long before ciprofloxacin works on UTI?
Ciprofloxacin usually works fast. You may begin to feel much better within 24 hours. The symptoms are usually gone by day three. Mild symptoms may persist for up to 5-7 days.
The eXtRa study  found that more than a third of the women taking Cipro XR (ciprofloxacin extended-release) for the treatment of uncomplicated urinary tract infections get significant improvement within just 3 hours of taking the antibiotic and half of the women reported symptom improvement within 6 hours. Additionally, 87% reported significant symptom improvement and 22% reported complete relief within 24 hours.
Does ciprofloxacin always cure UTI?
No. Ciprofloxacin may fail to cure urinary infection caused by resistant bacteria. Research indicates emerging ciproﬂoxacin resistance among bacteria causing urinary tract infections. UTI cases caused by E. coli resistant to ciprofloxacin account for about 17% .
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